Take a full-day adventure to the Andes on a guided coach traveling the famous Pan-American Highway. Head towards Aconcagua, the highest mountain in the Americas, then disembark to take in the area's stunning beauty and fresh air.

A comfortable, air-conditioned coach will collect you at your Mendoza hotel and head out for the Pan-American Highway. As you cruise towards the Chilean border, learn about the region's cultural and natural features through your expert guide's insightful commentary.

The urban architecture of Mendoza will give way to rolling wine country grape vines and eventually mountain peaks as you travel.

Potrerillos will be your first stop, where you can get some fresh air, purchase a snack, and admire the lake, the Embalse de Potrerillos.

Your next stop is Uspallata, a charming mountain town with abundant alpine views and an opportunity to purchase lunch. Back on the bus, you'll reach Puente del Inca about 60 minutes later. This natural rock bridge over the Vacas River was once visited by Charles Darwin, and its swirls of colored rock make for great photos.

There's a small community living nearby that has handmade native goods for sale. Continue heading west towards Chile's border and Aconcagua.

Argentina is the location of the largest mountain in the Americas, clocking in at 22,840 feet (6,960 meters.) The coach will stop at a scenic overlook for wonderful views and photo opportunities as the guide fills you in on information about the mountain itself.

Pichueta, a site of indigenous Huarpe ruins dating from the 5th century, is your last stop. After that the coach will head back down the Pan-American highway the way it came, delivering you back to your Mendoza hotel around 7 pm.

Relax at Termas de Cachueta, Argentina's only grotto sauna. Between using the outdoor and indoor natural thermal spas and mud baths, recline on the spa's plush lounge chairs and enjoy a delicious lunch of regional Creole specialties.

After pickup at your downtown Mendoza hotel, ride for approximately 60 minutes to Termas de Cachueta. Settle in to a state of deep relaxation before you even hit the thermal pools while enjoying views of the looming Andes and the sound of the Mendoza River rushing nearby.

On arrival, enjoy mountain terraces featuring glimmering thermal pools of fresh, naturally heated water. Take full advantage of all of the facilities during your daylong stay, including whirlpools, a hydrotherapy thermal circuit, foot baths and bubble beds. Inhale the bracing mountain air as you climb into hot, warm or cold baths.

Experience Argentina's only grotto sauna, letting the heat and mud detoxify your body and soften your skin. The natural solarium features Scottish- and Finnish-style showers for you to rinse off before eating lunch at a regional Creole buffet typically including vegetarian fare, a salad bar, barbecue pork and chicken, lamb, sausages and grilled vegetables.

Relax into a comfortable seat on your transport back to your Mendoza hotel at the end of a long day of indulgence and rejuvenation.

Discover the vineyards of Mendoza's wine region on this full-day guided tour. Learn about the winemaking process by visiting three different wineries in the Luján de Cuyo region with an informative wine-loving guide.

Taste several varietals, including the regional specialty, Malbec, and enjoy a picnic lunch and a visit to a local olive oil factory. Round-trip hotel transport by minivan is included.

Pedal through Mendoza's wine country on a bike, visiting three wineries, on this 6-hour guided tour. Learn about the winemaking process from a knowledgeable local guide while biking past rolling vineyards and soaking up the fresh air of Mendoza. 

Enjoy multiple tastings and a delicious lunch of regional Argentine specialties. Hotel pickup and drop-off included.

A thrilling horseback adventure from Mendoza to the heart of the Andes. Enjoy a 3.5-hour trail ride through the scenic Uco Valley, winding around the Cordón del Plata mountain range and climbing to a height of 9,185 feet (2,800 meters).

Your tour begins in the morning with hotel pickup in Mendoza. Aboard your comfortable minivan, drive through Villa Potrerillos, a village located 45 minutes away.

You’ll continue up to Quebrada del Condor, stopping at the panoramic viewpoint of Mirador de la Hoyada en route. Approximately two hours after leaving Mendoza you’ll reach the gorge, where a traditional Argentine breakfast is served to your small group.

Once your guide offers a safety briefing and some instruction, settle onto your sturdy horse — bred for stamina over mountainous terrain — and follow along the rugged trail.

Your 3.5-hour horseback ride starts at the foot of the Cordón del Plata, an Andean mountain range in the Uco Valley.

Amid this breath-taking landscape of snow-capped peaks, wildlife abounds. Keep a lookout for llamas, foxes, hares, condors and other incredible birds throughout your horseback ride.

In the middle of the journey, stop for a break at the shore of a creek to enjoy an infusion of mate, a popular drink made from yerba mate leaves steeped in hot water.

Then saddle up and follow ancient paths until your small group reaches a viewpoint. From 9,185 feet (2,800 meters) above sea level, you’ll appreciate the magnificent scenery, including the Cordón del Plata ridge and the Potrerillos Valley.

At the completion of your horseback ride in the late afternoon, dismount to enjoy an authentic Argentine asado (barbecue) for lunch. Your full-day tour ends with return transport by minivan to your hotel in Mendoza.